Domains within Homo sapiens protein Q9H9A5-6

Isoform 6 of CCR4-NOT transcription complex subunit 10

Alternative representations: 1 /

Protein length804 aa
Source databaseUniProt
Identifiers Q9H9A5-6, ENSP00000399862.2, ENSP00000399862
Source gene ENSG00000182973
Alternative splicing ENSP00000329376.6, CNO10_HUMAN, E9PCN5_HUMAN, H7C1X9_HUMAN, H7BZZ7_HUMAN, ENSP00000395385.1, Q9H9A5-6

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

Q9H9A5-6 is shown as CNOT10 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CNOT10

Protein Q9H9A5-6 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03018RNA degradation

KEGG orthologous groups

KONameDescription
K12607CNOT10CCR4-NOT transcription complex subunit 10

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000399862 in eggNOG.

OGTaxonomic classDescription
LKOG2471All organisms (root)CCR4-NOT transcription complex subunit 10,docosahexaenoic acid omega-hydroxylase [EC:1.14.14.79]
KOG2471Eukaryota (superkingdom)CCR4-NOT transcription complex subunit 10,docosahexaenoic acid omega-hydroxylase [EC:1.14.14.79]
HT1B3Metazoa (kingdom)CCR4-NOT transcription complex subunit 10,docosahexaenoic acid omega-hydroxylase [EC:1.14.14.79]
94FG4Chordata (phylum)CCR4-NOT transcription complex subunit 10
5RDAVSarcopterygii (superclass)CCR4-NOT transcription complex subunit 10
8Z21EMammalia (class)CCR4-NOT transcription complex subunit 10
4RFT6Euarchontoglires (superorder)CCR4-NOT transcription complex subunit 10
5026HPrimates (order)CCR4-NOT transcription complex subunit 10
98J27Haplorrhini (suborder)CCR4-NOT transcription complex subunit 10
BVE6USimiiformes (infraorder)CCR4-NOT transcription complex subunit 10
9F0KVCatarrhini (parvorder)CCR4-NOT transcription complex subunit 10
7KHM9Opisthokonta (clade)CCR4-NOT transcription complex subunit 10,docosahexaenoic acid omega-hydroxylase [EC:1.14.14.79]
9FF2NVertebrata (clade)CCR4-NOT transcription complex subunit 10
H3A69Bilateria (clade)CCR4-NOT transcription complex subunit 10,docosahexaenoic acid omega-hydroxylase [EC:1.14.14.79]
FX7NRHominoidea (superfamily)CCR4-NOT transcription complex subunit 10
5MXB5Hominidae (family)CCR4-NOT transcription complex subunit 10
5XUPVHomininae (subfamily)CCR4-NOT transcription complex subunit 10

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: