Domains within Homo sapiens protein Q9UBL0-3

Isoform 3 of cAMP-regulated phosphoprotein 21

Alternative representations: 1 /

Protein length813 aa
Source databaseUniProt
Identifiers Q9UBL0-3, ENSP00000412326.1, ENSP00000412326
Source gene ENSG00000172995
Alternative splicing C9J5R1_HUMAN, ENSP00000412411.1, ENSP00000398598.1, Q9UBL0-4, ENSP00000409808.1, ARP21_HUMAN, ENSP00000396324.1, ENSP00000409331.1, F8WDL2_HUMAN, ENSP00000413005.1, ENSP00000412341.1, C9JI74_HUMAN, Q9UBL0-3, H7C1B6_HUMAN, H7C2X8_HUMAN, H7C0P9_HUMAN, H7C3J7_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

Q9UBL0-3 is shown as ARPP21 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ARPP21

Protein Q9UBL0-3 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04320Dorso-ventral axis formation

KEGG orthologous groups

KONameDescription
K23713STAC3SH3 and cysteine-rich domain-containing protein 3

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000412326 in eggNOG.

OGTaxonomic classDescription
LKOG2953All organisms (root)SH3 and cysteine-rich domain-containing protein 3,a component of the cytoplasm (encore),SH3 and cysteine-rich domain-containing protein 2
KOG2953Eukaryota (superkingdom)SH3 and cysteine-rich domain-containing protein 3,a component of the cytoplasm (encore),SH3 and cysteine-rich domain-containing protein 2
HW51FMetazoa (kingdom)SH3 and cysteine-rich domain-containing protein 2,SH3 and cysteine-rich domain-containing protein 3,a component of the cytoplasm (encore)
947H6Chordata (phylum)R3H,SUZ,Myb_DNA-bind_4
5R7MZSarcopterygii (superclass)R3H,SUZ,Myb_DNA-bind_4
8YWEQMammalia (class)R3H,SUZ
4RJDJEuarchontoglires (superorder)R3H,SUZ
4ZMIVPrimates (order)R3H,SUZ
98R8VHaplorrhini (suborder)R3H,SUZ
BV7XBSimiiformes (infraorder)R3H,SUZ
9EYI6Catarrhini (parvorder)R3H,SUZ
7MSG5Opisthokonta (clade)SH3 and cysteine-rich domain-containing protein 2,SH3 and cysteine-rich domain-containing protein 3,a component of the cytoplasm (encore)
9G9B1Vertebrata (clade)R3H,SUZ,Myb_DNA-bind_4
H3D48Bilateria (clade)SH3 and cysteine-rich domain-containing protein 2,SH3 and cysteine-rich domain-containing protein 3,a component of the cytoplasm (encore)
FXEDWHominoidea (superfamily)R3H,SUZ
5N22DHominidae (family)R3H,SUZ
5XWI1Homininae (subfamily)R3H

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: