Domains within Drosophila melanogaster protein Q9XYR0_DROME (Q9XYR0)

LD20987p

Alternative representations: 1 /

Protein length486 aa
Source databaseUniProt
Identifiers Q9XYR0_DROME, Q9XYR0, FBPP0077119, A0A0J9QWH8_DROSI, A0A0J9QWH8
Source gene FBgn0026319
Alternative splicing Q9XYR0_DROME, A8DYU9_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

Q9XYR0_DROME is shown as Traf4 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Traf4

Protein Q9XYR0_DROME is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04657IL-17 signaling pathway
map05200Pathways in cancer

KEGG orthologous groups

KONameDescription
K09848TRAF4TNF receptor-associated factor 4

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0077119 in eggNOG.

OGTaxonomic classDescription
FV2NPmelanogaster group (species group)TNF receptor-associated factor 4
LKOG0297All organisms (root)TNF receptor-associated factor 4,ligand of Numb protein X 3/4 [EC:2.3.2.27],TNF receptor-associated factor 2 [EC:2.3.2.27]
EIW1REndopterygota (cohort)TNF receptor-associated factor 4
FE0NZmelanogaster subgroup (species subgroup)TNF receptor-associated factor 4
KOG0297Eukaryota (superkingdom)TNF receptor-associated factor 4,ligand of Numb protein X 3/4 [EC:2.3.2.27],TNF receptor-associated factor 2 [EC:2.3.2.27]
HSSE8Metazoa (kingdom)TNF receptor-associated factor 4,TNF receptor-associated factor 3
HHPQQArthropoda (phylum)TNF receptor-associated factor 4
85KJ5Hexapoda (subphylum)TNF receptor-associated factor 4
AH17WNeoptera (infraclass)TNF receptor-associated factor 4
ANDTKDiptera (order)TNF receptor-associated factor 4
7KARCOpisthokonta (clade)TNF receptor-associated factor 4,TNF receptor-associated factor 3
H3J2EBilateria (clade)TNF receptor-associated factor 4
EGZSUDrosophila (genus)TNF receptor-associated factor 4
50FI4Sophophora (subgenus)TNF receptor-associated factor 4

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: