Domains within Mus musculus protein RAB3C_MOUSE (P62823)

Ras-related protein Rab-3C

Alternative representations: 1 /

Protein length227 aa
Source databaseUniProt
Identifiers RAB3C_MOUSE, P62823, ENSMUSP00000132945.1, ENSMUSP00000132945, Q62858, Q62974, Q63482, Q9CXQ1, RAB3C_RAT, P62824, Q542T7_MOUSE, Q542T7
Source gene ENSMUSG00000021700
Alternative splicing RAB3C_MOUSE, A0A286YDR2_MOUSE, Q9CXS2_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

RAB3C_MOUSE is shown as Rab3c in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Rab3c

Protein RAB3C_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04721Synaptic vesicle cycle

KEGG orthologous groups

KONameDescription
K07882RAB3ARas-related protein Rab-3A
K07883RAB3CRas-related protein Rab-3C

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 27 PTMs annotated in this protein:

PTMCount
Phosphorylation18
Ubiquitination4
Prenylation2
Nitrosylation1
Methylation1
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Rab3c.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000132945 in eggNOG.

OGTaxonomic classDescription
LKOG0093All organisms (root)Ras-related protein Rab-3C,Ras-related protein Rab-3A,Ras-related protein Rab-3D
KOG0093Eukaryota (superkingdom)Ras-related protein Rab-3C,Ras-related protein Rab-3A,Ras-related protein Rab-3D
HUDBQMetazoa (kingdom)Ras-related protein Rab-3C,Ras-related protein Rab-3A,Ras-related protein Rab-3D
94IQMChordata (phylum)Ras-related protein Rab-3A,Ras-related protein Rab-3C,Ras-related protein Rab-3D
5QX83Sarcopterygii (superclass)Ras-related protein Rab-3C,Ras-related protein Rab-3B,Ras-related protein Rab-3A
8ZKRPMammalia (class)Ras-related protein Rab-3B,Ras-related protein Rab-3C,Ras-related protein Rab-3A
4RR1TEuarchontoglires (superorder)Ras-related protein Rab-3C
AHZ85Rodentia (order)Ras-related protein Rab-3C
8DCNRMyomorpha (suborder)Ras-related protein Rab-3C
H6S40Bilateria (clade)Ras-related protein Rab-3C,Ras-related protein Rab-3A,Ras-related protein Rab-3D
7NF17Opisthokonta (clade)Ras-related protein Rab-3C,Ras-related protein Rab-3A,Ras-related protein Rab-3D
9FY3ZVertebrata (clade)Ras-related protein Rab-3A,Ras-related protein Rab-3C,Ras-related protein Rab-3D
CQ5WBMuridae (family)Ras-related protein Rab-3C
ADZ9JMurinae (subfamily)Ras-related protein Rab-3C
5PX6RMus (genus)Ras-related protein Rab-3C
HED2JMus (subgenus)Ras-related protein Rab-3C

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: