Domains within Homo sapiens protein RAPSN_HUMAN (Q13702)

43 kDa receptor-associated protein of the synapse

Alternative representations: 1 /

Protein length412 aa
Source databaseUniProt
Identifiers RAPSN_HUMAN, Q13702, ENSP00000298854.2, ENSP00000298854, Q8TDF3, Q9BTD9, A0A0S2Z4F8_HUMAN, A0A0S2Z4F8
Source gene ENSG00000165917
Alternative splicing RAPSN_HUMAN, Q13702-2, E9PJP9_HUMAN, E9PK11_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Gnathostomata

Predicted functional partners

RAPSN_HUMAN is shown as RAPSN in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RAPSN

Protein RAPSN_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04360Axon guidance

KEGG orthologous groups

KONameDescription
K24924RAPSNreceptor-associated protein of the synapse

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 2 PTMs annotated in this protein:

PTMCount
Phosphorylation1
Myristoylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein RAPSN.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000298854 in eggNOG.

OGTaxonomic classDescription
LKOG1941All organisms (root)receptor-associated protein of the synapse,ephrin-B
KOG1941Eukaryota (superkingdom)receptor-associated protein of the synapse,ephrin-B
HSSTGMetazoa (kingdom)receptor-associated protein of the synapse
93KVDChordata (phylum)receptor-associated protein of the synapse
5QWH1Sarcopterygii (superclass)receptor-associated protein of the synapse
8ZCKYMammalia (class)receptor-associated protein of the synapse
4RIWNEuarchontoglires (superorder)receptor-associated protein of the synapse
4ZZD9Primates (order)receptor-associated protein of the synapse
98GSAHaplorrhini (suborder)receptor-associated protein of the synapse
BV75ASimiiformes (infraorder)receptor-associated protein of the synapse
9EVZUCatarrhini (parvorder)receptor-associated protein of the synapse
7IKQUOpisthokonta (clade)receptor-associated protein of the synapse
9FXYTVertebrata (clade)receptor-associated protein of the synapse
H5EIIBilateria (clade)receptor-associated protein of the synapse
FXFDBHominoidea (superfamily)receptor-associated protein of the synapse
5MY6KHominidae (family)receptor-associated protein of the synapse
5XUW6Homininae (subfamily)receptor-associated protein of the synapse

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: