Domains within Homo sapiens protein SBNO2_HUMAN (Q9Y2G9)

Protein strawberry notch homolog 2

Alternative representations: 1 /

Protein length1366 aa
Source databaseUniProt
Identifiers SBNO2_HUMAN, Q9Y2G9, ENSP00000354733.2, ENSP00000354733, ENSP00000488808.1, ENSP00000488808, ENSP00000477651.1, ENSP00000477651, A8K8P2, B3KWJ1, O75257, Q3KQX0, Q8TEM0, K7ENA9_HUMAN, K7ENA9, A0A2J8J2A2_PANTR, A0A2J8J2A2, K7ERL2_HUMAN, K7ERL2, A0A2J8J289_PANTR, A0A2J8J289
Source gene ENSG00000278788
Alternative splicing SBNO2_HUMAN, Q9Y2G9-3, K7ES28_HUMAN, ENSP00000468534.1, ENSP00000468302.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

SBNO2_HUMAN is shown as SBNO2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SBNO2

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 13 PTMs annotated in this protein:

PTMCount
Phosphorylation11
Methylation1
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein SBNO2.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000354733 in eggNOG.

OGTaxonomic classDescription
LKOG1513All organisms (root)AAA_34,Helicase_C_4,PHD
KOG1513Eukaryota (superkingdom)AAA_34,Helicase_C_4,PHD
HW9N6Metazoa (kingdom)AAA_34,Helicase_C_4,CDK2AP
93EDYChordata (phylum)AAA_34,Helicase_C_4,CDK2AP
5QBTJSarcopterygii (superclass)AAA_34,Helicase_C_4,CDK2AP
8Z2E8Mammalia (class)AAA_34,Helicase_C_4
4R2M3Euarchontoglires (superorder)AAA_34,Helicase_C_4
500ZJPrimates (order)AAA_34,Helicase_C_4
98D8RHaplorrhini (suborder)AAA_34,Helicase_C_4
BVAPNSimiiformes (infraorder)AAA_34,Helicase_C_4
9EWP0Catarrhini (parvorder)AAA_34,Helicase_C_4
H6VD5Bilateria (clade)AAA_34,Helicase_C_4,CDK2AP
9GC1DVertebrata (clade)AAA_34,Helicase_C_4,CDK2AP
7NXGPOpisthokonta (clade)AAA_34,Helicase_C_4,CDK2AP
FX7YSHominoidea (superfamily)AAA_34,Helicase_C_4
5NAF4Hominidae (family)AAA_34,Helicase_C_4
5Y2JXHomininae (subfamily)AAA_34,Helicase_C_4

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: