Domains within Homo sapiens protein SNP29_HUMAN (O95721)

Synaptosomal-associated protein 29

Alternative representations: 1 /

Protein length258 aa
Source databaseUniProt
Identifiers SNP29_HUMAN, O95721, ENSP00000215730.6, ENSP00000215730, C9JAF7_HUMAN, C9JAF7
Source gene ENSG00000099940
Alternative splicing SNP29_HUMAN, ENSP00000411095.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

SNP29_HUMAN is shown as SNAP29 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SNAP29

Protein SNP29_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04721Synaptic vesicle cycle
map04130SNARE interactions in vesicular transport

KEGG orthologous groups

KONameDescription
K08509SNAP29synaptosomal-associated protein 29
K18211SNAP25synaptosomal-associated protein 25

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 21 PTMs annotated in this protein:

PTMCount
Phosphorylation16
Acetylation3
Ubiquitination2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein SNAP29.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000215730 in eggNOG.

OGTaxonomic classDescription
LKOG3065All organisms (root)synaptosomal-associated protein 25,synaptosomal-associated protein 29,synaptosomal-associated protein 47
KOG3065Eukaryota (superkingdom)synaptosomal-associated protein 25,synaptosomal-associated protein 29,synaptosomal-associated protein 47
HW281Metazoa (kingdom)synaptosomal-associated protein 29
94Q6IChordata (phylum)synaptosomal-associated protein 29
5R1WJSarcopterygii (superclass)synaptosomal-associated protein 29
8ZEDCMammalia (class)synaptosomal-associated protein 29
4R5RXEuarchontoglires (superorder)synaptosomal-associated protein 29
504WZPrimates (order)synaptosomal-associated protein 29
98IUGHaplorrhini (suborder)synaptosomal-associated protein 29
BVBY8Simiiformes (infraorder)synaptosomal-associated protein 29
9EFYPCatarrhini (parvorder)synaptosomal-associated protein 29
9FAGNVertebrata (clade)synaptosomal-associated protein 29
H532MBilateria (clade)synaptosomal-associated protein 29
7IJ3EOpisthokonta (clade)synaptosomal-associated protein 29
FX7EYHominoidea (superfamily)synaptosomal-associated protein 29
5ND7EHominidae (family)synaptosomal-associated protein 29
5Y5ACHomininae (subfamily)synaptosomal-associated protein 29

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: