Domains within Homo sapiens protein STRN3_HUMAN (Q13033)

Striatin-3

Alternative representations: 1 /

Protein length797 aa
Source databaseUniProt
Identifiers STRN3_HUMAN, Q13033, ENSP00000350071.5, ENSP00000350071, A2RTX7, A6NHZ7, Q9NRA5
Source gene ENSG00000196792
Alternative splicing Q13033-2, STRN3_HUMAN, G3V340_HUMAN, ENSP00000452542.1, H0YJT2_HUMAN, ENSP00000451233.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

STRN3_HUMAN is shown as STRN3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for STRN3

Protein STRN3_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04013MAPK signaling pathway - fly

KEGG orthologous groups

KONameDescription
K17608STRN1_3_4striatin 1/3/4

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 30 PTMs annotated in this protein:

PTMCount
Phosphorylation21
Ubiquitination4
Acetylation4
Nitrosylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein STRN3.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000350071 in eggNOG.

OGTaxonomic classDescription
LKOG0642All organisms (root)striatin 1/3/4,WD repeat-containing protein 64,WD repeat-containing protein 49
KOG0642Eukaryota (superkingdom)striatin 1/3/4,WD repeat-containing protein 64,WD repeat-containing protein 49
HUXFJMetazoa (kingdom)striatin 1/3/4
93H7AChordata (phylum)striatin 1/3/4
5QGKWSarcopterygii (superclass)striatin 1/3/4
8ZFP2Mammalia (class)striatin 1/3/4
4RBZFEuarchontoglires (superorder)striatin 1/3/4
4ZYBWPrimates (order)striatin 1/3/4
986DSHaplorrhini (suborder)striatin 1/3/4
BUY0FSimiiformes (infraorder)striatin 1/3/4
9EYKSCatarrhini (parvorder)striatin 1/3/4
H5VX5Bilateria (clade)striatin 1/3/4
9GA0QVertebrata (clade)striatin 1/3/4
7N3R1Opisthokonta (clade)striatin 1/3/4
FXAKHHominoidea (superfamily)striatin 1/3/4
5ND5XHominidae (family)striatin 1/3/4
5XVV9Homininae (subfamily)striatin 1/3/4

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: