Domains within Drosophila melanogaster protein SYDE_DROME (Q9V9S7)

Rho GTPase-activating protein 100F

Alternative representations: 1 /

Protein length1866 aa
Source databaseUniProt
Identifiers SYDE_DROME, Q9V9S7, FBPP0291391, C3KGQ2, E1JJ30, E1JJ31, Q8SWW5
Source gene FBgn0039883
Alternative splicing A0A0B4K813_DROME, A0A0B4LJ24_DROME, I0C0N0_DROME, A0A0B4K7S3_DROME, A0A0B4K6W5_DROME, A0A0B4K7G3_DROME, Q9V9S7-2, SYDE_DROME

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

SYDE_DROME is shown as RhoGAP100F in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RhoGAP100F

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7227.FBpp0291391 in eggNOG.

OGTaxonomic classDescription
EJ08SEndopterygota (cohort)Rho GTPase-activating protein SYDE
FV53Smelanogaster group (species group)Rho GTPase-activating protein SYDE
LKOG1452All organisms (root)Rho GTPase-activating protein SYDE,cytospin
FE4PZmelanogaster subgroup (species subgroup)Rho GTPase-activating protein SYDE
KOG1452Eukaryota (superkingdom)Rho GTPase-activating protein SYDE,cytospin
HUGMQMetazoa (kingdom)Rho GTPase-activating protein SYDE
HIKXSArthropoda (phylum)Rho GTPase-activating protein SYDE
85ZJJHexapoda (subphylum)Rho GTPase-activating protein SYDE
AGWKNNeoptera (infraclass)Rho GTPase-activating protein SYDE
AP0KMDiptera (order)Rho GTPase-activating protein SYDE
7N3P9Opisthokonta (clade)Rho GTPase-activating protein SYDE,cytospin
H5QRDBilateria (clade)Rho GTPase-activating protein SYDE
EGYI0Drosophila (genus)Rho GTPase-activating protein SYDE
50EMKSophophora (subgenus)Rho GTPase-activating protein SYDE

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: