Domains within Homo sapiens protein TM182_HUMAN (Q6ZP80)

Transmembrane protein 182

Alternative representations: 1 /

Protein length229 aa
Source databaseUniProt
Identifiers TM182_HUMAN, Q6ZP80, ENSP00000394178.2, ENSP00000394178, C9JML7, Q3B7B8, Q53TT9, Q6GMU0, Q8WW45, Q96NR4, Q6ZP80-2, Q6ZP80-3
Source gene ENSG00000170417
Alternative splicing A0A1W2PQA2_HUMAN, ENSP00000392106.1, ENSP00000387258.1, B8ZZ71_HUMAN, A0A1W2PS41_HUMAN, TM182_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

TM182_HUMAN is shown as TMEM182 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for TMEM182

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000394178 in eggNOG.

OGTaxonomic classDescription
6WHJCAll organisms (root)Claudin_2
5F3MXEukaryota (superkingdom)Claudin_2
HVAHTMetazoa (kingdom)Claudin_2
94FS4Chordata (phylum)Claudin_2
5R47DSarcopterygii (superclass)Claudin_2
8Z82WMammalia (class)Claudin_2
4RQJWEuarchontoglires (superorder)Claudin_2
4ZRDNPrimates (order)Claudin_2
98KS6Haplorrhini (suborder)Claudin_2
BVBRCSimiiformes (infraorder)Claudin_2
9ETUZCatarrhini (parvorder)Claudin_2
H5K1WBilateria (clade)Claudin_2
9GN7FVertebrata (clade)Claudin_2
7NNSFOpisthokonta (clade)Claudin_2
FX3DGHominoidea (superfamily)Claudin_2
5N5QKHominidae (family)Claudin_2
5Y1BQHomininae (subfamily)Claudin_2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: