Domains within Caenorhabditis elegans protein U4PRH0_CAEEL (U4PRH0)

Uncharacterized protein

Alternative representations: 1 /

Protein length1533 aa
Source databaseUniProt
Identifiers U4PRH0_CAEEL, U4PRH0, F54E7.3I
Source gene WBGene00003918
Alternative splicing Q17353-2, PAR3_CAEEL, Q17353-3, U4PRG6_CAEEL, U4PEL6_CAEEL, U4PBE2_CAEEL, U4PBR8_CAEEL, U4PM75_CAEEL, U4PRH0_CAEEL, U4PEM0_CAEEL, U4PBE6_CAEEL, U4PBS3_CAEEL, U4PM79_CAEEL

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

U4PRH0_CAEEL is shown as par-3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for par-3

Protein U4PRH0_CAEEL is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05165Human papillomavirus infection
map04530Tight junction

KEGG orthologous groups

KONameDescription
K04237PARD3partitioning defective protein 3
K10692LNX1_2ligand of Numb protein X 1/2 [EC:2.3.2.27]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 6239.F54E7.3i.1 in eggNOG.

OGTaxonomic classDescription
LKOG3528All organisms (root)ligand of Numb protein X 1/2 [EC:2.3.2.27],syntenin-1,intraflagellar transport protein 20
KOG3528Eukaryota (superkingdom)ligand of Numb protein X 1/2 [EC:2.3.2.27],syntenin-1,intraflagellar transport protein 20
HVEU5Metazoa (kingdom)partitioning defective protein 3
8B6MENematoda (phylum)partitioning defective protein 3
HCTREChromadorea (class)partitioning defective protein 3
6DSUURhabditida (order)partitioning defective protein 3
8PSMGRhabditina (suborder)partitioning defective protein 3
H5A47Bilateria (clade)partitioning defective protein 3
7MNZKOpisthokonta (clade)partitioning defective protein 3
AYDVCRhabditidae (family)partitioning defective protein 3
BT338Caenorhabditis (genus)partitioning defective protein 3

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: