Domains within Mus musculus protein UPAR_MOUSE (P35456)

Urokinase plasminogen activator surface receptor

Alternative representations: 1 /

Protein length327 aa
Source databaseUniProt
Identifiers UPAR_MOUSE, P35456, ENSMUSP00000002284.9, ENSMUSP00000002284, P35457, Q545X5_MOUSE, Q545X5
Source gene ENSMUSG00000046223
Alternative splicing UPAR_MOUSE, A0A0U1RNF3_MOUSE, A0A0U1RNN0_MOUSE

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eutheria

Predicted functional partners

UPAR_MOUSE is shown as Plaur in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Plaur

Protein UPAR_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04610Complement and coagulation cascades

KEGG orthologous groups

KONameDescription
K03985PLAUR, CD87plasminogen activator, urokinase receptor

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 6 PTMs annotated in this protein:

PTMCount
N-linked glycosylation5
Phosphorylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein Plaur.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000002284 in eggNOG.

OGTaxonomic classDescription
73BU3All organisms (root)plasminogen activator, urokinase receptor,lymphocyte antigen 6 complex locus protein D/E/F/G6/H
5JFTKEukaryota (superkingdom)plasminogen activator, urokinase receptor,lymphocyte antigen 6 complex locus protein D/E/F/G6/H
HTSV9Metazoa (kingdom)plasminogen activator, urokinase receptor,lymphocyte antigen 6 complex locus protein D/E/F/G6/H
940NIChordata (phylum)plasminogen activator, urokinase receptor
5QUYRSarcopterygii (superclass)plasminogen activator, urokinase receptor
8ZH71Mammalia (class)plasminogen activator, urokinase receptor
4RFX5Euarchontoglires (superorder)plasminogen activator, urokinase receptor
AIAGRRodentia (order)plasminogen activator, urokinase receptor
8D8ZEMyomorpha (suborder)plasminogen activator, urokinase receptor
9FCV0Vertebrata (clade)plasminogen activator, urokinase receptor
H6X7MBilateria (clade)plasminogen activator, urokinase receptor,lymphocyte antigen 6 complex locus protein D/E/F/G6/H
7HJMFOpisthokonta (clade)plasminogen activator, urokinase receptor,lymphocyte antigen 6 complex locus protein D/E/F/G6/H
CQ7UWMuridae (family)plasminogen activator, urokinase receptor
AE3HGMurinae (subfamily)plasminogen activator, urokinase receptor
5PQ95Mus (genus)plasminogen activator, urokinase receptor
HE2H3Mus (subgenus)plasminogen activator, urokinase receptor

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: