Domains within Homo sapiens protein VTM2L_HUMAN (Q96N03)

V-set and transmembrane domain-containing protein 2-like protein

Alternative representations: 1 /

Protein length204 aa
Source databaseUniProt
Identifiers VTM2L_HUMAN, Q96N03, ENSP00000362560.4, ENSP00000362560, E1P5V7, Q5JWZ4, Q5JWZ5, Q8ND45, Q9BR37, F7BBN4_MACMU, F7BBN4, A0A2K5UVZ4_MACFA, A0A2K5UVZ4, A0A0D9RMN7_CHLSB, A0A0D9RMN7, A0A2K6DV57_MACNE, A0A2K6DV57, A0A2I3MDW7_PAPAN, A0A2I3MDW7
Source gene ENSG00000132821
Alternative splicing VTM2L_HUMAN, ENSP00000362558.4, ENSP00000406537.1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

VTM2L_HUMAN is shown as VSTM2L in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for VSTM2L

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Phosphorylation4

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein VSTM2L.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000362560 in eggNOG.

OGTaxonomic classDescription
75KHEAll organisms (root)V-set and transmembrane domain-containing protein 2
5FE6JEukaryota (superkingdom)V-set and transmembrane domain-containing protein 2
HSS1AMetazoa (kingdom)V-set and transmembrane domain-containing protein 2
94F1AChordata (phylum)V-set and transmembrane domain-containing protein 2
5QR7DSarcopterygii (superclass)V-set and transmembrane domain-containing protein 2
8Z2X3Mammalia (class)V-set and transmembrane domain-containing protein 2
4RCZWEuarchontoglires (superorder)V-set and transmembrane domain-containing protein 2
4ZQXQPrimates (order)V-set and transmembrane domain-containing protein 2
98BF4Haplorrhini (suborder)V-set and transmembrane domain-containing protein 2
BVHPNSimiiformes (infraorder)V-set and transmembrane domain-containing protein 2
9EMH9Catarrhini (parvorder)V-set and transmembrane domain-containing protein 2
H3QFHBilateria (clade)V-set and transmembrane domain-containing protein 2
9FX0BVertebrata (clade)V-set and transmembrane domain-containing protein 2
7J513Opisthokonta (clade)V-set and transmembrane domain-containing protein 2
FX5UGHominoidea (superfamily)V-set and transmembrane domain-containing protein 2
5MXUVHominidae (family)V-set and transmembrane domain-containing protein 2
5XVXKHomininae (subfamily)V-set and transmembrane domain-containing protein 2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: