Domains within Homo sapiens protein ZC3HD_HUMAN (Q5T200)

Zinc finger CCCH domain-containing protein 13

Alternative representations: 1 /

Protein length1668 aa
Source databaseUniProt
Identifiers ZC3HD_HUMAN, Q5T200, ENSP00000242848.4, ENSP00000242848, A2A323, O94936, Q5T1Z9, Q7Z7J3, Q8NDT6, Q9H0L6
Source gene ENSG00000123200
Alternative splicing ZC3HD_HUMAN, Q5T200-2, A0A087WX14_HUMAN, Q5T9K0_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

ZC3HD_HUMAN is shown as ZC3H13 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ZC3H13

Protein ZC3HD_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03040Spliceosome

KEGG orthologous groups

KONameDescription
K12879THOC2THO complex subunit 2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000242848 in eggNOG.

OGTaxonomic classDescription
LKOG1874All organisms (root)THO complex subunit 2,zinc finger CCCH domain-containing protein 13
KOG1874Eukaryota (superkingdom)THO complex subunit 2,zinc finger CCCH domain-containing protein 13
HU171Metazoa (kingdom)zinc finger CCCH domain-containing protein 13
93PCMChordata (phylum)zinc finger CCCH domain-containing protein 13
5RDDTSarcopterygii (superclass)zinc finger CCCH domain-containing protein 13
8ZHVNMammalia (class)zinc finger CCCH domain-containing protein 13
4RPSNEuarchontoglires (superorder)zinc finger CCCH domain-containing protein 13
503ZQPrimates (order)zinc finger CCCH domain-containing protein 13
987MIHaplorrhini (suborder)zinc finger CCCH domain-containing protein 13
BVDK0Simiiformes (infraorder)zinc finger CCCH domain-containing protein 13
9EFG3Catarrhini (parvorder)zinc finger CCCH domain-containing protein 13
H6UUMBilateria (clade)zinc finger CCCH domain-containing protein 13
9FF97Vertebrata (clade)zinc finger CCCH domain-containing protein 13
7K9C5Opisthokonta (clade)zinc finger CCCH domain-containing protein 13
FXEP0Hominoidea (superfamily)zinc finger CCCH domain-containing protein 13
5NA38Hominidae (family)zinc finger CCCH domain-containing protein 13
5Y803Homininae (subfamily)zinc finger CCCH domain-containing protein 13

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: