Domains within Danio rerio protein A5PLA1_DANRE (A5PLA1)

RAB39B, member RAS oncogene family a

Alternative representations: 1 /

Protein length213 aa
Source databaseUniProt
Identifiers A5PLA1_DANRE, A5PLA1, ENSDARP00000020538.4, ENSDARP00000020538
Source gene ENSDARG00000019312

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

A5PLA1_DANRE is shown as rab39ba in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for rab39ba

Protein A5PLA1_DANRE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05132Salmonella infection
map05014Amyotrophic lateral sclerosis

KEGG orthologous groups

KONameDescription
K07925RAB39BRas-related protein Rab-39B
K07904RAB11ARas-related protein Rab-11A

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 3 PTMs annotated in this protein:

PTMCount
Phosphorylation2
Ubiquitination1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ENSDARG00000019312.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 7955.ENSDARP00000020538 in eggNOG.

OGTaxonomic classDescription
9IH2NOtomorpha (cohort)Ras-related protein Rab-39B
LCOG1100All organisms (root)Ras-related protein Rab-11A,Ras-related C3 botulinum toxin substrate 1,ADP-ribosylation factor 1/2
5HABIEukaryota (superkingdom)Ras-related protein Rab-39B
HW1DPMetazoa (kingdom)Ras-related protein Rab-39B
94Q12Chordata (phylum)Ras-related protein Rab-39B
FXTUQActinopterygii (superclass)Ras-related protein Rab-39B
8NBNDNeopterygii (subclass)Ras-related protein Rab-39B
7HGV7Opisthokonta (clade)Ras-related protein Rab-39B
H3MWSBilateria (clade)Ras-related protein Rab-39B
9FFANVertebrata (clade)Ras-related protein Rab-39B
BEYXACyprinidae (family)Ras-related protein Rab-39B

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: