Domains within Bacillus pumilus SAFR-032 protein A8FAX8_BACP2 (A8FAX8)

Transcriptional regulator

Alternative representations: 1 /

Protein length232 aa
Source databaseUniProt
Identifiers A0A200HID3_BACPU, A0A200HID3, A8FAX8_BACP2, A8FAX8

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

A8FAX8_BACP2 is shown as BPUM_0708 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for BPUM_0708

Protein A8FAX8_BACP2 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system

KEGG orthologous groups

KONameDescription
K07702dpiA, citBtwo-component system, CitB family, response regulator CitB
K11638K11638, citTtwo-component system, CitB family, response regulator CitT

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 315750.BPUM_0708 in eggNOG.

OGTaxonomic classDescription
LCOG4565All organisms (root)two-component system, CitB family, response regulator CitB,two-component system, CitB family, response regulator MalR,two-component system, CitB family, response regulator DctR
COG4565Bacteria (superkingdom)two-component system, CitB family, response regulator CitB,two-component system, CitB family, response regulator MalR,two-component system, CitB family, response regulator DctR
9X9SDFirmicutes (phylum)two-component system, CitB family, response regulator CitT,two-component system, CitB family, response regulator,two-component system, CitB family, response regulator MalR
G4ZPTBacilli (class)two-component system, CitB family, response regulator CitT,two-component system, CitB family, response regulator
F1XMEBacillales (order)two-component system, CitB family, response regulator CitT,two-component system, CitB family, response regulator
F60KUBacillaceae (family)two-component system, CitB family, response regulator CitT
AB0M5Bacillus (genus)two-component system, CitB family, response regulator CitT

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: