Domains within Bacillus pumilus SAFR-032 protein A8FG29_BACP2 (A8FG29)

Two-component response regulator

Alternative representations: 1 /

Protein length245 aa
Source databaseUniProt
Identifiers A8FG29_BACP2, A8FG29

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

A8FG29_BACP2 is shown as BPUM_2535 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for BPUM_2535

Protein A8FG29_BACP2 is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system

KEGG orthologous groups

KONameDescription
K02477K02477two-component system, LytTR family, response regulator
K07705lytT, lytRtwo-component system, LytTR family, response regulator LytT

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 315750.BPUM_2535 in eggNOG.

OGTaxonomic classDescription
LCOG3279All organisms (root)two-component system, LytTR family, response regulator,two-component system, LytTR family, response regulator LytT,two-component system, LytTR family, response regulator AlgR
COG3279Bacteria (superkingdom)two-component system, LytTR family, response regulator,two-component system, LytTR family, response regulator LytT,two-component system, LytTR family, response regulator AlgR
9XRDNFirmicutes (phylum)two-component system, LytTR family, response regulator LytT,two-component system, LytTR family, response regulator AgrA,two-component system, LytTR family, response regulator
G5PF4Bacilli (class)two-component system, LytTR family, response regulator LytT,two-component system, LytTR family, response regulator,two-component system, LytTR family, response regulator NatR
F2UQVBacillales (order)two-component system, LytTR family, response regulator LytT
F655BBacillaceae (family)two-component system, LytTR family, response regulator LytT
AAQ80Bacillus (genus)two-component system, LytTR family, response regulator LytT

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: