Domains within Homo sapiens protein C2D4D_HUMAN (B7Z1M9)

C2 calcium-dependent domain-containing protein 4D

Alternative representations: 1 /

Protein length353 aa
Source databaseUniProt
Identifiers C2D4D_HUMAN, B7Z1M9, ENSP00000389554.1, ENSP00000389554, B2RXG8
Source gene ENSG00000225556

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

C2D4D_HUMAN is shown as C2CD4D in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for C2CD4D

Protein C2D4D_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04721Synaptic vesicle cycle

KEGG orthologous groups

KONameDescription
K17598SYTLsynaptotagmin-like protein

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000389554 in eggNOG.

OGTaxonomic classDescription
LKOG1028All organisms (root)synaptotagmin-like protein,synaptotagmin-14/16,synaptotagmin-1
KOG1028Eukaryota (superkingdom)synaptotagmin-like protein,synaptotagmin-14/16,synaptotagmin-1
HV678Metazoa (kingdom)C2,UQ_con,SWIRM-assoc_2
93ZPUChordata (phylum)C2
5QCYJSarcopterygii (superclass)C2
8YUXNMammalia (class)C2
4RDC8Euarchontoglires (superorder)C2
501VFPrimates (order)C2
98HAUHaplorrhini (suborder)C2
BV7FASimiiformes (infraorder)C2
9EFIFCatarrhini (parvorder)C2
H71I6Bilateria (clade)C2,UQ_con,SWIRM-assoc_2
7MY4IOpisthokonta (clade)C2,UQ_con,SWIRM-assoc_2
9FF05Vertebrata (clade)C2
FWYM6Hominoidea (superfamily)C2
5NC4FHominidae (family)C2
5Y342Homininae (subfamily)C2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: