Domains within Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 protein B8IYK1_DESDA (B8IYK1)

Two component, sigma54 specific, transcriptional regulator, Fis family

Alternative representations: 1 /

Protein length505 aa
Source databaseUniProt
Identifiers A0A1K1PP46_DESDE, A0A1K1PP46, B8IYK1_DESDA, B8IYK1

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bacteria

Predicted functional partners

B8IYK1_DESDA is shown as Ddes_2381 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ddes_2381

Protein B8IYK1_DESDA is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map02020Two-component system
map02040Flagellar assembly

KEGG orthologous groups

KONameDescription
K10943flrC, fleR, flaMtwo-component system, response regulator FlrC
K07714atoCtwo-component system, NtrC family, response regulator AtoC
K07712glnG, ntrCtwo-component system, NtrC family, nitrogen regulation response regulator GlnG

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 525146.Ddes_2381 in eggNOG.

OGTaxonomic classDescription
LCOG2204All organisms (root)two-component system, NtrC family, nitrogen regulation response regulator GlnG,two-component system, NtrC family, response regulator AtoC,two-component system, NtrC family, nitrogen regulation response regulator NtrX
COG2204Bacteria (superkingdom)two-component system, NtrC family, nitrogen regulation response regulator GlnG,two-component system, NtrC family, response regulator AtoC,two-component system, NtrC family, nitrogen regulation response regulator NtrX
5Z77YProteobacteria (phylum)two-component system, NtrC family, nitrogen regulation response regulator GlnG,two-component system, NtrC family, C4-dicarboxylate transport response regulator DctD,two-component system, NtrC family, nitrogen regulation response regulator NtrX
A2CE0delta/epsilon subdivisions (subphylum)two-component system, NtrC family, response regulator AtoC,two-component system, NtrC family, response regulator,two-component system, NtrC family, response regulator HydG
F7AAZDeltaproteobacteria (class)two-component system, NtrC family, response regulator AtoC,two-component system, NtrC family, response regulator HydG,two-component system, NtrC family, response regulator
CCAWGDesulfovibrionales (order)two-component system, response regulator FlrC
B7MFADesulfovibrionaceae (family)two-component system, response regulator FlrC
88X59Desulfovibrio (genus)two-component system, response regulator FlrC
5NTRMDesulfovibrio desulfuricans (species)two-component system, response regulator FlrC

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: