Domains within Desulfovibrio desulfuricans subsp. desulfuricans str. ATCC 27774 protein B8J1W5_DESDA (B8J1W5)

Transcriptional regulator, ArsR family

Alternative representations: 1 /

Protein length307 aa
Source databaseUniProt
Identifiers B8J1W5_DESDA, B8J1W5

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

B8J1W5_DESDA is shown as Ddes_0040 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Ddes_0040

Protein B8J1W5_DESDA is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05208Chemical carcinogenesis - reactive oxygen species

KEGG orthologous groups

KONameDescription
K03183ubiEdemethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201] iPath3
K03892arsRArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 525146.Ddes_0040 in eggNOG.

OGTaxonomic classDescription
LCOG0640All organisms (root)ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor,ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor,ArsR family transcriptional regulator, zinc-responsive transcriptional repressor
LCOG2226All organisms (root)demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201],malonyl-CoA O-methyltransferase [EC:2.1.1.197],23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]
COG2226Bacteria (superkingdom)demethylmenaquinone methyltransferase / 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase [EC:2.1.1.163 2.1.1.201],malonyl-CoA O-methyltransferase [EC:2.1.1.197],23S rRNA (guanine745-N1)-methyltransferase [EC:2.1.1.187]
COG0640Bacteria (superkingdom)ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor,ArsR family transcriptional regulator, lead/cadmium/zinc/bismuth-responsive transcriptional repressor,ArsR family transcriptional regulator, zinc-responsive transcriptional repressor
625NFProteobacteria (phylum)ArsR family transcriptional regulator, arsenate/arsenite/antimonite-responsive transcriptional repressor / arsenate reductase (thioredoxin) [EC:1.20.4.4]
A2B7Ddelta/epsilon subdivisions (subphylum)Methyltransf_11,HTH_5,HTH_20
F6XEEDeltaproteobacteria (class)Methyltransf_11,HTH_5,HTH_20
CCFJGDesulfovibrionales (order)HTH_5,Methyltransf_11,HTH_20
B7GETDesulfovibrionaceae (family)HTH_5,Methyltransf_11,HTH_20
890UDDesulfovibrio (genus)HTH_5,Methyltransf_11,HTH_20
5NT2BDesulfovibrio desulfuricans (species)HTH_5,Methyltransf_11

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: