Domains within Bos taurus protein F1N726_BOVIN (F1N726)

Glycoprotein 2

Alternative representations: 1 /

Protein length534 aa
Source databaseUniProt
Identifiers F1N726_BOVIN, F1N726, ENSBTAP00000008217.4, ENSBTAP00000008217, L8IK54_9CETA, L8IK54
Source gene ENSBTAG00000006263

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

F1N726_BOVIN is shown as GP2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for GP2

Protein F1N726_BOVIN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05165Human papillomavirus infection
map04970Salivary secretion

KEGG orthologous groups

KONameDescription
K18274UMODuromodulin
K00430E1.11.1.7peroxidase [EC:1.11.1.7] iPath3
K04659THBS2Sthrombospondin 2/3/4/5
Some of these orthologous groups are included in the interactive Pathways Explorer overview maps. Select an overview map and click the button below to highlight them in iPath.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9913.ENSBTAP00000008217 in eggNOG.

OGTaxonomic classDescription
7553HAll organisms (root)peroxidase [EC:1.11.1.7],transmembrane channel-like protein,thrombospondin 2/3/4/5
KOG1217Eukaryota (superkingdom)peroxidase [EC:1.11.1.7],transmembrane channel-like protein,thrombospondin 2/3/4/5
HSY91Metazoa (kingdom)thrombospondin 2/3/4/5,delta,matrilin
93F39Chordata (phylum)uromodulin,pancreatic secretory granule membrane major glycoprotein GP2,deleted in malignant brain tumors 1 protein
5R2KCSarcopterygii (superclass)pancreatic secretory granule membrane major glycoprotein GP2,uromodulin
8ZB23Mammalia (class)pancreatic secretory granule membrane major glycoprotein GP2,uromodulin
BQSHYLaurasiatheria (superorder)pancreatic secretory granule membrane major glycoprotein GP2
AXDETArtiodactyla (order)pancreatic secretory granule membrane major glycoprotein GP2
B60QAPecora (infraorder)pancreatic secretory granule membrane major glycoprotein GP2
H4QFHBilateria (clade)thrombospondin 2/3/4/5,delta,matrilin
9FVMWVertebrata (clade)uromodulin,pancreatic secretory granule membrane major glycoprotein GP2,deleted in malignant brain tumors 1 protein
7NXWDOpisthokonta (clade)thrombospondin 2/3/4/5,delta,matrilin
7PKBYBovidae (family)pancreatic secretory granule membrane major glycoprotein GP2
DATDQBovinae (subfamily)pancreatic secretory granule membrane major glycoprotein GP2
AZN52Bos (genus)pancreatic secretory granule membrane major glycoprotein GP2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: