Domains within Homo sapiens protein GPIX_HUMAN (P14770)

Platelet glycoprotein IX

Alternative representations: 1 /

Protein length177 aa
Source databaseUniProt
Identifiers GPIX_HUMAN, P14770, ENSP00000303942.4, ENSP00000303942, Q14445, Q8N1D1, Q92525, D1MER8_HUMAN, D1MER8
Source gene ENSG00000169704

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Amniota

Predicted functional partners

GPIX_HUMAN is shown as GP9 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for GP9

Protein GPIX_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04512ECM-receptor interaction
map04514Cell adhesion molecules

KEGG orthologous groups

KONameDescription
K22038LRRC8volume-regulated anion channel
K06263GP9, CD42aplatelet glycoprotein IX

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000303942 in eggNOG.

OGTaxonomic classDescription
LCOG1552All organisms (root)volume-regulated anion channel,leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein,protein phosphatase 1 regulatory subunit 7
KOG0619Eukaryota (superkingdom)volume-regulated anion channel,leucine-rich repeat and immunoglobulin-like domain-containing nogo receptor-interacting protein,leucine-rich repeat transmembrane protein FLRT
HT9VIMetazoa (kingdom)platelet glycoprotein IX
93YHAChordata (phylum)platelet glycoprotein IX
5RC89Sarcopterygii (superclass)platelet glycoprotein IX
8ZIUTMammalia (class)platelet glycoprotein IX
4RPHBEuarchontoglires (superorder)platelet glycoprotein IX
4ZU2KPrimates (order)platelet glycoprotein IX
9896WHaplorrhini (suborder)platelet glycoprotein IX
BUZEXSimiiformes (infraorder)platelet glycoprotein IX
9EGUWCatarrhini (parvorder)platelet glycoprotein IX
7KRQQOpisthokonta (clade)platelet glycoprotein IX
9G4ZVVertebrata (clade)platelet glycoprotein IX
H528KBilateria (clade)platelet glycoprotein IX
FX7GDHominoidea (superfamily)platelet glycoprotein IX
5NBIAHominidae (family)platelet glycoprotein IX
5XT7PHomininae (subfamily)platelet glycoprotein IX

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: