Domains within Homo sapiens protein IF4E_HUMAN (P06730)

Eukaryotic translation initiation factor 4E

Alternative representations: 1 /

Protein length217 aa
Source databaseUniProt
Identifiers IF4E_HUMAN, P06730, ENSP00000389624.2, ENSP00000389624, B7Z6V1, D6RCQ6, Q96E95, G2HH86_PANTR, G2HH86, H9ENS9_MACMU, H9ENS9, I7GAS4_MACFA, I7GAS4, A0A2J8TQQ5_PONAB, A0A2J8TQQ5, A0A0D9QVU1_CHLSB, A0A0D9QVU1, A0A2K6M3I5_RHIBE, A0A2K6M3I5, A0A2K6AUV9_MACNE, A0A2K6AUV9, A0A2K6PUJ2_RHIRO, A0A2K6PUJ2, A0A2K5JHE0_COLAP, A0A2K5JHE0, A0A2I2YJ03_GORGO, A0A2I2YJ03
Source gene ENSG00000151247
Alternative splicing IF4E_HUMAN, P06730-3, D6RFJ3_HUMAN, H0Y8J7_HUMAN, D6RBW1_HUMAN, ENSP00000425561.1

Predicted functional partners

IF4E_HUMAN is shown as EIF4E in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for EIF4E

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 60711.ENSCSAP00000000480 in eggNOG.

OGTaxonomic classDescription
LKOG1670All organisms (root)translation initiation factor 4E,cellulose synthase A [EC:2.4.1.12]
KOG1670Eukaryota (superkingdom)translation initiation factor 4E,cellulose synthase A [EC:2.4.1.12]
HUMBMMetazoa (kingdom)translation initiation factor 4E
94DWGChordata (phylum)translation initiation factor 4E
5QKHNSarcopterygii (superclass)translation initiation factor 4E
8Z9FJMammalia (class)translation initiation factor 4E
4RIQ5Euarchontoglires (superorder)translation initiation factor 4E
501Q0Primates (order)translation initiation factor 4E
98RHDHaplorrhini (suborder)translation initiation factor 4E
7MQ77Opisthokonta (clade)translation initiation factor 4E
9FHHQVertebrata (clade)translation initiation factor 4E
H5PM6Bilateria (clade)translation initiation factor 4E

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: