Domains within Homo sapiens protein NDP_HUMAN (Q00604)

Norrin

Alternative representations: 1 /

Protein length133 aa
Source databaseUniProt
Identifiers NDP_HUMAN, Q00604, ENSP00000495972.1, ENSP00000495972, ENSP00000367301.5, ENSP00000367301, ENSP00000495811.1, ENSP00000495811, B2R8K6, Q5JYH5, NDP_MACFA, Q60HE4, Q4R4Y3, F7DMF6_MACMU, F7DMF6, H2PVD4_PONAB, H2PVD4, G3RCG7_GORGO, G3RCG7, G7Q2J7_MACFA, G7Q2J7, A0A0D9RN84_CHLSB, A0A0D9RN84, A0A2K6L720_RHIBE, A0A2K6L720, A0A2K6CUV6_MACNE, A0A2K6CUV6, A0A2K5LUG5_CERAT, A0A2K5LUG5, A0A2K6PPV1_RHIRO, A0A2K6PPV1, A0A096MXU0_PAPAN, A0A096MXU0, A0A2K5K2B0_COLAP, A0A2K5K2B0, A0A2K6AE33_MANLE, A0A2K6AE33
Source gene ENSG00000124479

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

NDP_HUMAN is shown as NDP in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for NDP

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 2 PTMs annotated in this protein:

PTMCount
Phosphorylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ENSMMUG00000018001.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000495811 in eggNOG.

OGTaxonomic classDescription
7553KAll organisms (root)pectinesterase [EC:3.1.1.11],Rho family-interacting cell polarization regulator,calcineurin-binding protein cabin-1
KOG1216Eukaryota (superkingdom)pectinesterase [EC:3.1.1.11],Rho family-interacting cell polarization regulator,calcineurin-binding protein cabin-1
HV4DHMetazoa (kingdom)norrin
93XWZChordata (phylum)norrin
5QRYQSarcopterygii (superclass)norrin
8ZIHBMammalia (class)norrin
4RCF1Euarchontoglires (superorder)norrin
4ZTBAPrimates (order)norrin
98KNMHaplorrhini (suborder)norrin
BV14BSimiiformes (infraorder)norrin
9EJZ3Catarrhini (parvorder)norrin
9FPKCVertebrata (clade)norrin
H3GTSBilateria (clade)norrin
7GHAUOpisthokonta (clade)norrin
FXCIDHominoidea (superfamily)norrin
5N3CVHominidae (family)norrin
5XZU5Homininae (subfamily)norrin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: