Domains within Homo sapiens protein SSX4_HUMAN (O60224)

Protein SSX4

Alternative representations: 1 /

Protein length188 aa
Source databaseUniProt
Identifiers SSX4_HUMAN, O60224, ENSP00000469011.1, ENSP00000469011, ENSP00000469394.1, ENSP00000469394, A8MYD4, B2RPE3, Q3SYD4, Q5JQZ0, Q9UJU9
Source gene ENSG00000268009
Alternative splicing SSX4_HUMAN, O60224-2

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

SSX4_HUMAN is shown as SSX4 in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for SSX4

Protein SSX4_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05202Transcriptional misregulation in cancer

KEGG orthologous groups

KONameDescription
K15624SSXprotein SSX

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 18 PTMs annotated in this protein:

PTMCount
Acetylation10
Phosphorylation4
Ubiquitination4

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ENSG00000198946.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000469011 in eggNOG.

OGTaxonomic classDescription
71TTJAll organisms (root)protein SSX1,protein SSX2,prothymosin alpha
5IPFDEukaryota (superkingdom)protein SSX1,protein SSX2,prothymosin alpha
HV2Z8Metazoa (kingdom)protein SSX1,protein SSX2,prothymosin alpha
93V3MChordata (phylum)protein SSX1,protein SSX2,prothymosin alpha
5R6RPSarcopterygii (superclass)protein SSX1,protein SSX2,prothymosin alpha
8ZMM1Mammalia (class)protein SSX1,protein SSX2,prothymosin alpha
4RGGZEuarchontoglires (superorder)protein SSX1,protein SSX2,prothymosin alpha
4ZKG6Primates (order)protein SSX1,protein SSX2
98DEKHaplorrhini (suborder)protein SSX1
BV3YWSimiiformes (infraorder)protein SSX1
9ES1TCatarrhini (parvorder)protein SSX1
9G8SMVertebrata (clade)protein SSX1,protein SSX2,prothymosin alpha
H4CDKBilateria (clade)protein SSX1,protein SSX2,prothymosin alpha
7HQAPOpisthokonta (clade)protein SSX1,protein SSX2,prothymosin alpha
FXCPWHominoidea (superfamily)protein SSX1
5N3V8Hominidae (family)protein SSX1
5Y3TTHomininae (subfamily)protein SSX1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: