Domains within Xenopus laevis protein BRAC_XENLA (P24781)

Brachyury protein

Alternative representations: 1 /

Protein length432 aa
Source databaseUniProt
Identifiers Q6IP86, A0A1L8G2B1_XENLA, A0A1L8G2B1, BRAC_XENLA, P24781

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Metazoa

Predicted functional partners

BRAC_XENLA is shown as tbxt in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for tbxt

Protein BRAC_XENLA is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04013MAPK signaling pathway - fly
map04977Vitamin digestion and absorption
map05321Inflammatory bowel disease

KEGG orthologous groups

KONameDescription
K10172BRA, Tbrachyury protein
K10180TBX6T-box protein 6

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 8355.A0A1L8G2B1 in eggNOG.

OGTaxonomic classDescription
LKOG3585All organisms (root)T-box protein 6,T-box protein 2,brachyury protein
KOG3585Eukaryota (superkingdom)T-box protein 6,T-box protein 2,brachyury protein
HUCH5Metazoa (kingdom)brachyury protein,T-box protein 19,T-box protein 6
94V9UChordata (phylum)brachyury protein,T-box protein 19
5QWGFSarcopterygii (superclass)brachyury protein,T-box protein 19
7IR4YOpisthokonta (clade)brachyury protein,T-box protein 19,T-box protein 21
9GIGNVertebrata (clade)brachyury protein,T-box protein 19
H49V7Bilateria (clade)brachyury protein,T-box protein 19,T-box protein 6

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: