Domains within Homo sapiens protein TAGL_HUMAN (Q01995)

Transgelin

Alternative representations: 1 /

Protein length201 aa
Source databaseUniProt
Identifiers TAGL_HUMAN, Q01995, ENSP00000376678.4, ENSP00000376678, ENSP00000432054.1, ENSP00000432054, ENSP00000278968.6, ENSP00000278968, ENSP00000431941.1, ENSP00000431941, ENSP00000432282.1, ENSP00000432282, O15542, G3REJ2_GORGO, G3REJ2, A0A2I3SQC8_PANTR, A0A2I3SQC8, Q5U0D2_HUMAN, Q5U0D2, H2Q4U6_PANTR, H2Q4U6, H2NFE5_PONAB, H2NFE5, A0A2I2YBG4_GORGO, A0A2I2YBG4, A0A2K6GVG6_PROCO, A0A2K6GVG6, G1R6Y3_NOMLE, G1R6Y3
Source gene ENSG00000149591
Alternative splicing TAGL_HUMAN, ENSP00000431862.1, H0YCU9_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

TAGL_HUMAN is shown as TAGLN in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for TAGLN

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 76 PTMs annotated in this protein:

PTMCount
Phosphorylation34
Acetylation20
Ubiquitination14
Methylation6
Nitrosylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ENSPTRG00000004320.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000376678 in eggNOG.

OGTaxonomic classDescription
LKOG2046All organisms (root)transgelin,cilia- and flagella-associated protein 45,tripartite motif-containing protein 43/48/49/64/77
KOG2046Eukaryota (superkingdom)transgelin,cilia- and flagella-associated protein 45,tripartite motif-containing protein 43/48/49/64/77
HVAVVMetazoa (kingdom)transgelin
945CWChordata (phylum)transgelin
5QGUYSarcopterygii (superclass)transgelin
8YYYBMammalia (class)transgelin
4RIXMEuarchontoglires (superorder)transgelin
5006JPrimates (order)transgelin
98P2GHaplorrhini (suborder)transgelin
BVBMTSimiiformes (infraorder)transgelin
9ENT3Catarrhini (parvorder)transgelin
H6KWMBilateria (clade)transgelin
7MBEEOpisthokonta (clade)transgelin
9GT1UVertebrata (clade)transgelin
FX6TWHominoidea (superfamily)transgelin
5N089Hominidae (family)transgelin
5Y8XTHomininae (subfamily)transgelin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: