Domains within Homo sapiens protein CC181_HUMAN (Q5TID7)

Coiled-coil domain-containing protein 181

Alternative representations: 1 /

Protein length509 aa
Source databaseUniProt
Identifiers CC181_HUMAN, Q5TID7, ENSP00000356780.3, ENSP00000356780, O60780, Q53FD5, Q5TID9, Q8TC48, X6RJ50_HUMAN, X6RJ50
Source gene ENSG00000117477
Alternative splicing CC181_HUMAN, Q5TID7-3, Q5TID7-2, ENSP00000411000.1

Predicted functional partners

CC181_HUMAN is shown as CCDC181 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CCDC181

Protein CC181_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04977Vitamin digestion and absorption

KEGG orthologous groups

KONameDescription
K14610SLC19A2_3, THTRsolute carrier family 19 (thiamine transporter), member 2/3

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000356780 in eggNOG.

OGTaxonomic classDescription
LKOG3810All organisms (root)solute carrier family 19 (thiamine transporter), member 2/3,solute carrier family 19 (folate transporter), member 1,coiled-coil domain-containing protein 181
KOG3810Eukaryota (superkingdom)solute carrier family 19 (thiamine transporter), member 2/3,solute carrier family 19 (folate transporter), member 1,coiled-coil domain-containing protein 181
HTWIZMetazoa (kingdom)coiled-coil domain-containing protein 181
93R82Chordata (phylum)coiled-coil domain-containing protein 181
5R6G0Sarcopterygii (superclass)coiled-coil domain-containing protein 181
8Z9E4Mammalia (class)coiled-coil domain-containing protein 181
4R6JVEuarchontoglires (superorder)coiled-coil domain-containing protein 181
4ZK1RPrimates (order)coiled-coil domain-containing protein 181
98N9QHaplorrhini (suborder)coiled-coil domain-containing protein 181
BV4B8Simiiformes (infraorder)coiled-coil domain-containing protein 181
9EH4NCatarrhini (parvorder)coiled-coil domain-containing protein 181
7NDWZOpisthokonta (clade)coiled-coil domain-containing protein 181
H3GNNBilateria (clade)coiled-coil domain-containing protein 181
9GNCAVertebrata (clade)coiled-coil domain-containing protein 181
FX3BEHominoidea (superfamily)coiled-coil domain-containing protein 181
5N8W2Hominidae (family)coiled-coil domain-containing protein 181
5Y0Y4Homininae (subfamily)coiled-coil domain-containing protein 181

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: