Domains within Mus musculus protein WF15A_MOUSE (Q8BH89)

WAP four-disulfide core domain protein 15A

Alternative representations: 1 /

Protein length80 aa
Source databaseUniProt
Identifiers WF15A_MOUSE, Q8BH89, ENSMUSP00000070718.2, ENSMUSP00000070718
Source gene ENSMUSG00000051769

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

WF15A_MOUSE is shown as Wfdc15a in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for Wfdc15a

Protein WF15A_MOUSE is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05215Prostate cancer

KEGG orthologous groups

KONameDescription
K23087TFPI2tissue factor pathway inhibitor 2

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 10090.ENSMUSP00000070718 in eggNOG.

OGTaxonomic classDescription
LKOG4295All organisms (root)tissue factor pathway inhibitor 2,Kunitz-type protease inhibitor 1,tissue factor pathway inhibitor
KOG4295Eukaryota (superkingdom)tissue factor pathway inhibitor 2,Kunitz-type protease inhibitor 1,tissue factor pathway inhibitor
HSPY9Metazoa (kingdom)WAP
946SDChordata (phylum)WAP
5QQKQSarcopterygii (superclass)WAP
8ZA4TMammalia (class)WAP
4RQRMEuarchontoglires (superorder)WAP
AIGG9Rodentia (order)WAP
8DEGQMyomorpha (suborder)WAP
H3KM5Bilateria (clade)WAP
7M8PQOpisthokonta (clade)WAP
9GHPTVertebrata (clade)WAP
CQCCVMuridae (family)WAP
AE0ZGMurinae (subfamily)WAP
5PM46Mus (genus)WAP
HEA2QMus (subgenus)WAP

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: