Domains within Homo sapiens protein RB40A_HUMAN (Q8WXH6)

Ras-related protein Rab-40A

Alternative representations: 1 /

Protein length277 aa
Source databaseUniProt
Identifiers RB40A_HUMAN, Q8WXH6, ENSP00000305648.1, ENSP00000305648, ENSP00000361716.1, ENSP00000361716, O00407, Q17RQ5, Q6DK06, Q8TF06
Source gene ENSG00000172476

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

RB40A_HUMAN is shown as RAB40A in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RAB40A

Protein RB40A_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04144Endocytosis

KEGG orthologous groups

KONameDescription
K07901RAB8A, MELRas-related protein Rab-8A

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 2 PTMs annotated in this protein:

PTMCount
Phosphorylation1
Ubiquitination1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein RAB40A.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000361716 in eggNOG.

OGTaxonomic classDescription
LKOG0078All organisms (root)Ras-related protein Rab-8A,Ras and EF-hand domain-containing protein,Ras-related protein Rab-40
KOG0078Eukaryota (superkingdom)Ras-related protein Rab-8A,Ras and EF-hand domain-containing protein,Ras-related protein Rab-40
HSMUBMetazoa (kingdom)Ras-related protein Rab-40
94DQNChordata (phylum)Ras-related protein Rab-40
5QTJRSarcopterygii (superclass)Ras-related protein Rab-40
8ZC1UMammalia (class)Ras-related protein Rab-40
4RRASEuarchontoglires (superorder)Ras-related protein Rab-40
4ZK84Primates (order)Ras-related protein Rab-40
H5WY1Bilateria (clade)Ras-related protein Rab-40
7J0BXOpisthokonta (clade)Ras-related protein Rab-40
9G34AVertebrata (clade)Ras-related protein Rab-40

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: