Domains within Homo sapiens protein TBA4B_HUMAN (Q9H853)

Putative tubulin-like protein alpha-4B

Alternative representations: 1 /

Protein length241 aa
Source databaseUniProt
Identifiers TBA4B_HUMAN, Q9H853, ENSP00000487719.1, ENSP00000487719
Source gene ENSG00000243910

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

TBA4B_HUMAN is shown as TUBA4B in the network

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The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for TUBA4B

Protein TBA4B_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05016Huntington disease

KEGG orthologous groups

KONameDescription
K07374TUBAtubulin alpha

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000487719 in eggNOG.

OGTaxonomic classDescription
LKOG1376All organisms (root)tubulin alpha,tubulin beta,small subunit ribosomal protein S34
KOG1376Eukaryota (superkingdom)tubulin alpha,tubulin beta,small subunit ribosomal protein S34
HUI0YMetazoa (kingdom)tubulin alpha,sialidase-1 [EC:3.2.1.18],ganglioside-induced differentiation-associated protein 1
94D5GChordata (phylum)tubulin alpha,sialidase-1 [EC:3.2.1.18],ganglioside-induced differentiation-associated protein 1
5RAVASarcopterygii (superclass)tubulin alpha,DnaJ homolog subfamily B member 2,peroxin-26
8Z3Y7Mammalia (class)tubulin alpha
4RNQ7Euarchontoglires (superorder)Tubulin
500U8Primates (order)Tubulin
98AGPHaplorrhini (suborder)Tubulin
BV9B7Simiiformes (infraorder)Tubulin
9EXN8Catarrhini (parvorder)Tubulin
7N6RPOpisthokonta (clade)tubulin alpha,sialidase-1 [EC:3.2.1.18],ganglioside-induced differentiation-associated protein 1
H3C98Bilateria (clade)tubulin alpha,sialidase-1 [EC:3.2.1.18],ganglioside-induced differentiation-associated protein 1
9FGE9Vertebrata (clade)tubulin alpha,ganglioside-induced differentiation-associated protein 1,DnaJ homolog subfamily B member 2
FXCXYHominoidea (superfamily)Tubulin
5N3ATHominidae (family)Tubulin
5Y84CHomininae (subfamily)Tubulin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: