Domains within Homo sapiens protein ZMAT4_HUMAN (Q9H898)

Zinc finger matrin-type protein 4

Alternative representations: 1 /

Protein length229 aa
Source databaseUniProt
Identifiers ZMAT4_HUMAN, Q9H898, ENSP00000297737.6, ENSP00000297737, Q8WUT8, A0A2K5DH65_AOTNA, A0A2K5DH65, A0A2K6S8P4_SAIBB, A0A2K6S8P4, H9EP70_MACMU, H9EP70, G3QUT1_GORGO, G3QUT1, A0A2K5VFZ1_MACFA, A0A2K5VFZ1, A0A2K6KWG5_RHIBE, A0A2K6KWG5, A0A2K6DQH5_MACNE, A0A2K6DQH5, A0A2K5P5U0_CERAT, A0A2K5P5U0, A0A2K6R0W9_RHIRO, A0A2K6R0W9, A0A096N635_PAPAN, A0A096N635, A0A2K5QTH2_CEBCA, A0A2K5QTH2, A0A2K5YY58_MANLE, A0A2K5YY58, G1RPU3_NOMLE, G1RPU3
Source gene ENSG00000165061
Alternative splicing ENSP00000319785.7, ZMAT4_HUMAN, ENSP00000428423.1, E5RGZ7_HUMAN, E5RFW2_HUMAN

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Bilateria

Predicted functional partners

ZMAT4_HUMAN is shown as ZMAT4 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ZMAT4

Protein ZMAT4_HUMAN is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04115p53 signaling pathway

KEGG orthologous groups

KONameDescription
K10137ZMAT3zinc finger, matrin type 3

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 8 PTMs annotated in this protein:

PTMCount
Phosphorylation6
Ubiquitination2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein ENSMMUG00000000776.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 9606.ENSP00000297737 in eggNOG.

OGTaxonomic classDescription
77V85All organisms (root)zinc finger, matrin type 3,cholinesterase [EC:3.1.1.8]
5EU68Eukaryota (superkingdom)zinc finger, matrin type 3,cholinesterase [EC:3.1.1.8]
HVF2KMetazoa (kingdom)zf-met,zf-C2H2_jaz
946TIChordata (phylum)zf-met,zf-C2H2_jaz
5RBV6Sarcopterygii (superclass)zf-met,zf-C2H2_jaz
8YY5JMammalia (class)zf-met,zf-C2H2_jaz
4R6V2Euarchontoglires (superorder)zf-met,zf-C2H2_jaz
4ZM9HPrimates (order)zf-met
98CKFHaplorrhini (suborder)zf-met
BVHD0Simiiformes (infraorder)zf-met
9EI89Catarrhini (parvorder)zf-met
H4X5RBilateria (clade)zf-met,zf-C2H2_jaz
9GM0DVertebrata (clade)zf-met,zf-C2H2_jaz
7HSIUOpisthokonta (clade)zf-met,zf-C2H2_jaz

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: