Domains within Saccharomyces cerevisiae protein YBR059C

Alternative representations: 1 /

Protein length1108 aa
Source databaseEnsembl
Identifiers YBR059C
Source gene YBR059C

Predicted functional partners

YBR059C is shown as AKL1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for AKL1

Protein YBR059C is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05202Transcriptional misregulation in cancer

KEGG orthologous groups

KONameDescription
K08853AAKAP2-associated kinase [EC:2.7.11.1]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 31 PTMs annotated in this protein:

PTMCount
Phosphorylation29
Ubiquitination2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AKL1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YBR059C in eggNOG.

OGTaxonomic classDescription
FQICQDikarya (subkingdom)AP2-associated kinase [EC:2.7.11.1],protein-serine/threonine kinase [EC:2.7.11.-]
LKOG1989All organisms (root)AP2-associated kinase [EC:2.7.11.1],cyclin G-associated kinase [EC:2.7.11.1],BMP2 inducible kinase [EC:2.7.11.1]
KOG1989Eukaryota (superkingdom)AP2-associated kinase [EC:2.7.11.1],cyclin G-associated kinase [EC:2.7.11.1],BMP2 inducible kinase [EC:2.7.11.1]
BNUJGFungi (kingdom)AP2-associated kinase [EC:2.7.11.1],protein-serine/threonine kinase [EC:2.7.11.-]
9SS6UAscomycota (phylum)protein-serine/threonine kinase [EC:2.7.11.-],AP2-associated kinase [EC:2.7.11.1]
91P5DSaccharomycetales (order)protein-serine/threonine kinase [EC:2.7.11.-],AP2-associated kinase [EC:2.7.11.1]
7HQ04Opisthokonta (clade)AP2-associated kinase [EC:2.7.11.1],BMP2 inducible kinase [EC:2.7.11.1],protein-serine/threonine kinase [EC:2.7.11.-]
AT96GSaccharomycetaceae (family)protein-serine/threonine kinase [EC:2.7.11.-]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: