Domains within Saccharomyces cerevisiae protein YDR373W

Alternative representations: 1 /

Protein length190 aa
Source databaseEnsembl
Identifiers YDR373W
Source gene YDR373W

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

YDR373W is shown as FRQ1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for FRQ1

Protein YDR373W is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map03020RNA polymerase
map04740Olfactory transduction
map04744Phototransduction
map04626Plant-pathogen interaction

KEGG orthologous groups

KONameDescription
K19932NCS1neuronal calcium sensor
K13448CMLcalcium-binding protein CML
K23855KCNIPKv channel-interacting protein

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 12 PTMs annotated in this protein:

PTMCount
Ubiquitination5
Phosphorylation4
Nitrosylation1
Myristoylation1
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_45880.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YDR373W in eggNOG.

OGTaxonomic classDescription
FQX1QDikarya (subkingdom)neuronal calcium sensor 1,DNA-directed RNA polymerase II subunit RPB9
LCOG5126All organisms (root)calcium-binding protein CML,calmodulin,serine/threonine-protein phosphatase 2B regulatory subunit
KOG0044Eukaryota (superkingdom)Kv channel-interacting protein,guanylate cyclase activator 1,neuronal calcium sensor 1
BQ4BTFungi (kingdom)neuronal calcium sensor 1,DNA-directed RNA polymerase II subunit RPB9
9TDPUAscomycota (phylum)neuronal calcium sensor 1,DNA-directed RNA polymerase II subunit RPB9
91CMWSaccharomycetales (order)neuronal calcium sensor 1
7JWDHOpisthokonta (clade)neuronal calcium sensor 1,hippocalcin-like protein 1,neurocalcin delta
AT5CASaccharomycetaceae (family)neuronal calcium sensor 1

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: