Domains within Saccharomyces cerevisiae protein YDR524C

Alternative representations: 1 /

Protein length482 aa
Source databaseEnsembl
Identifiers YDR524C
Source gene YDR524C

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

YDR524C is shown as AGE1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for AGE1

Protein YDR524C is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04666Fc gamma R-mediated phagocytosis
map04144Endocytosis

KEGG orthologous groups

KONameDescription
K12488ASAPArf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
K12489ACAPArf-GAP with coiled-coil, ANK repeat and PH domain-containing protein

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Phosphorylation3
Nitration1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AGE1.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YDR524C in eggNOG.

OGTaxonomic classDescription
LKOG0521All organisms (root)Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein,Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein,DCC-interacting protein 13 alpha
KOG0521Eukaryota (superkingdom)Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein,Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein,DCC-interacting protein 13 alpha
BKR46Fungi (kingdom)Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein
7IMR7Opisthokonta (clade)Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: