Domains within Saccharomyces cerevisiae protein YER155C

Alternative representations: 1 /

Protein length2167 aa
Source databaseEnsembl
Identifiers YER155C
Source gene YER155C

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Saccharomycetaceae

Predicted functional partners

YER155C is shown as BEM2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for BEM2

Protein YER155C is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04011MAPK signaling pathway - yeast

KEGG orthologous groups

KONameDescription
K19844BEM2GTPase-activating protein BEM2
K20636ARHGAP12_27Rho GTPase-activating protein 12/27
K20643RGD1Rho GTPase-activating protein RGD1

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 24 PTMs annotated in this protein:

PTMCount
Phosphorylation24

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_52250.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YER155C in eggNOG.

OGTaxonomic classDescription
FPW1DDikarya (subkingdom)GTPase-activating protein BEM2
LKOG1450All organisms (root)Rho GTPase-activating protein 12/27,Rho GTPase-activating protein 15,Rho GTPase-activating protein SYDE
KOG1450Eukaryota (superkingdom)Rho GTPase-activating protein 12/27,Rho GTPase-activating protein 15,Rho GTPase-activating protein SYDE
BNDC1Fungi (kingdom)Rho GTPase-activating protein RGD1,GTPase-activating protein BEM2
9SY20Ascomycota (phylum)GTPase-activating protein BEM2
91KBESaccharomycetales (order)GTPase-activating protein BEM2
7NZ0VOpisthokonta (clade)Rho GTPase-activating protein 12/27,Rho GTPase-activating protein 15,Rho GTPase-activating protein RGD1
AT6K1Saccharomycetaceae (family)GTPase-activating protein BEM2

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: