Domains within Saccharomyces cerevisiae protein YFR037C

Alternative representations: 1 /

Protein length557 aa
Source databaseEnsembl
Identifiers YFR037C
Source gene YFR037C

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

YFR037C is shown as RSC8 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for RSC8

Protein YFR037C is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05225Hepatocellular carcinoma

KEGG orthologous groups

KONameDescription
K11649SMARCCSWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 8 PTMs annotated in this protein:

PTMCount
Ubiquitination5
Phosphorylation2
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_61020.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YFR037C in eggNOG.

OGTaxonomic classDescription
LKOG1279All organisms (root)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C,histone H2A deubiquitinase [EC:3.4.19.-],chromatin structure-remodeling complex subunit RSC8
FRP5ZDikarya (subkingdom)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C,SWI/SNF complex subunit SWI3,chromatin structure-remodeling complex subunit RSC8
KOG1279Eukaryota (superkingdom)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C,histone H2A deubiquitinase [EC:3.4.19.-],chromatin structure-remodeling complex subunit RSC8
BPGVCFungi (kingdom)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C,SWI/SNF complex subunit SWI3,chromatin structure-remodeling complex subunit RSC8
9U4SHAscomycota (phylum)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C,SWI/SNF complex subunit SWI3,chromatin structure-remodeling complex subunit RSC8
91M5ZSaccharomycetales (order)chromatin structure-remodeling complex subunit RSC8
7MXCZOpisthokonta (clade)SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C,SWI/SNF complex subunit SWI3,chromatin structure-remodeling complex subunit RSC8
AT4XVSaccharomycetaceae (family)chromatin structure-remodeling complex subunit RSC8

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: