Domains within Saccharomyces cerevisiae protein YGR080W

Alternative representations: 1 /

Protein length332 aa
Source databaseEnsembl
Identifiers YGR080W
Source gene YGR080W

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

YGR080W is shown as TWF1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for TWF1

Protein YGR080W is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map05203Viral carcinogenesis

KEGG orthologous groups

KONameDescription
K08870TWFtwinfilin

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Phosphorylation4

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_73030.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YGR080W in eggNOG.

OGTaxonomic classDescription
FPSMKDikarya (subkingdom)twinfilin,V-type H+-transporting ATPase subunit d
LKOG1747All organisms (root)twinfilin,COMPASS component SWD2,V-type H+-transporting ATPase subunit d
KOG1747Eukaryota (superkingdom)twinfilin,COMPASS component SWD2,V-type H+-transporting ATPase subunit d
BJZXCFungi (kingdom)twinfilin,V-type H+-transporting ATPase subunit d
9U8UUAscomycota (phylum)twinfilin
91IMGSaccharomycetales (order)twinfilin
7MU6GOpisthokonta (clade)twinfilin,COMPASS component SWD2,V-type H+-transporting ATPase subunit d
AT8SGSaccharomycetaceae (family)twinfilin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: