Domains within Saccharomyces cerevisiae protein YJL095W

Alternative representations: 1 /

Protein length1478 aa
Source databaseEnsembl
Identifiers YJL095W
Source gene YJL095W

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

YJL095W is shown as BCK1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for BCK1

Protein YJL095W is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04912GnRH signaling pathway
map04010MAPK signaling pathway
map04139Mitophagy - yeast
map04011MAPK signaling pathway - yeast

KEGG orthologous groups

KONameDescription
K11229BCK1mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
K04421MAP3K3, MEKK3mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K11228STE11mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 15 PTMs annotated in this protein:

PTMCount
Phosphorylation15

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_101030.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YJL095W in eggNOG.

OGTaxonomic classDescription
LKOG0198All organisms (root)mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase 17/18,MKL/myocardin-like protein
FR4GYDikarya (subkingdom)mitogen-activated protein kinase kinase kinase ANP1 [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
KOG0198Eukaryota (superkingdom)mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase 17/18,MKL/myocardin-like protein
BKH05Fungi (kingdom)mitogen-activated protein kinase kinase kinase [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase ANP1 [EC:2.7.11.25]
9SEK2Ascomycota (phylum)mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
91JRBSaccharomycetales (order)mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
7MM7FOpisthokonta (clade)mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
AT7DNSaccharomycetaceae (family)mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: