Domains within Saccharomyces cerevisiae protein YKL010C

Alternative representations: 1 /

Protein length1483 aa
Source databaseEnsembl
Identifiers YKL010C
Source gene YKL010C

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Eukaryota

Predicted functional partners

YKL010C is shown as UFD4 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for UFD4

Protein YKL010C is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04120Ubiquitin mediated proteolysis

KEGG orthologous groups

KONameDescription
K10590TRIP12E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 7 PTMs annotated in this protein:

PTMCount
Phosphorylation7

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein EC1118_1K5_2454g.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YKL010C in eggNOG.

OGTaxonomic classDescription
FQIMEDikarya (subkingdom)E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
LKOG0168All organisms (root)E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26],protein KIBRA,other hect domain ubiquitin protein ligase E3 [EC:2.3.2.26]
LKOG0170All organisms (root)E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26],ubiquitin fusion degradation protein 1,other hect domain ubiquitin protein ligase E3 [EC:2.3.2.26]
KOG0168Eukaryota (superkingdom)E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26],other hect domain ubiquitin protein ligase E3 [EC:2.3.2.26],ubiquitin fusion degradation protein 1
KOG0170Eukaryota (superkingdom)E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26],ubiquitin fusion degradation protein 1,other hect domain ubiquitin protein ligase E3 [EC:2.3.2.26]
BPUH0Fungi (kingdom)E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
9SZR0Ascomycota (phylum)E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
91MTNSaccharomycetales (order)E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
7MSGPOpisthokonta (clade)E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]
AT7C8Saccharomycetaceae (family)E3 ubiquitin-protein ligase TRIP12 [EC:2.3.2.26]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: