Domains within Saccharomyces cerevisiae protein YKL101W

Alternative representations: 1 /

Protein length1518 aa
Source databaseEnsembl
Identifiers YKL101W
Source gene YKL101W

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

YKL101W is shown as HSL1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for HSL1

Protein YKL101W is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04111Cell cycle - yeast

KEGG orthologous groups

KONameDescription
K02515HSL1serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]
K08796BRSKBR serine/threonine kinase [EC:2.7.11.1]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YKL101W in eggNOG.

OGTaxonomic classDescription
LKOG0588All organisms (root)BR serine/threonine kinase [EC:2.7.11.1],serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-],serine/threonine-protein kinase GIN4 [EC:2.7.11.-]
FQ6Q6Dikarya (subkingdom)serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-],serine/threonine-protein kinase GIN4 [EC:2.7.11.-],5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
KOG0588Eukaryota (superkingdom)BR serine/threonine kinase [EC:2.7.11.1],serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-],serine/threonine-protein kinase GIN4 [EC:2.7.11.-]
BK208Fungi (kingdom)serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-],serine/threonine-protein kinase GIN4 [EC:2.7.11.-],5'-AMP-activated protein kinase, catalytic alpha subunit [EC:2.7.11.11]
9U8E3Ascomycota (phylum)serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-],serine/threonine-protein kinase GIN4 [EC:2.7.11.-],BR serine/threonine kinase [EC:2.7.11.1]
91GAGSaccharomycetales (order)serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]
7KKC0Opisthokonta (clade)BR serine/threonine kinase [EC:2.7.11.1],serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-],serine/threonine-protein kinase GIN4 [EC:2.7.11.-]
AT989Saccharomycetaceae (family)serine/threonine-protein kinase HSL1, negative regulator of Swe1 kinase [EC:2.7.11.-]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: