Domains within Saccharomyces cerevisiae protein YLR362W

Alternative representations: 1 /

Protein length717 aa
Source databaseEnsembl
Identifiers YLR362W
Source gene YLR362W

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

Predicted functional partners

YLR362W is shown as STE11 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for STE11

Protein YLR362W is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04912GnRH signaling pathway
map04010MAPK signaling pathway
map04011MAPK signaling pathway - yeast

KEGG orthologous groups

KONameDescription
K04421MAP3K3, MEKK3mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
K11228STE11mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 7 PTMs annotated in this protein:

PTMCount
Phosphorylation6
Ubiquitination1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein EC1118_1L7_2333g.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YLR362W in eggNOG.

OGTaxonomic classDescription
LKOG0198All organisms (root)mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase 17/18,MKL/myocardin-like protein
FQDG6Dikarya (subkingdom)mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
KOG0198Eukaryota (superkingdom)mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase 17/18,MKL/myocardin-like protein
BKH05Fungi (kingdom)mitogen-activated protein kinase kinase kinase [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase ANP1 [EC:2.7.11.25]
9UVBQAscomycota (phylum)mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
91E60Saccharomycetales (order)mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
7MM7FOpisthokonta (clade)mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase 2 [EC:2.7.11.25]
AT98CSaccharomycetaceae (family)mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: