Domains within Saccharomyces cerevisiae protein YMR001C

Alternative representations: 1 /

Protein length705 aa
Source databaseEnsembl
Identifiers YMR001C
Source gene YMR001C

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of cellular organisms

Predicted functional partners

YMR001C is shown as CDC5 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for CDC5

Protein YMR001C is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04111Cell cycle - yeast
map04068FoxO signaling pathway

KEGG orthologous groups

KONameDescription
K06631PLK1polo-like kinase 1 [EC:2.7.11.21]
K06660CDC5cell cycle serine/threonine-protein kinase CDC5/MSD2 [EC:2.7.11.21]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 14 PTMs annotated in this protein:

PTMCount
Phosphorylation12
Ubiquitination2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein CDC5.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YMR001C in eggNOG.

OGTaxonomic classDescription
LKOG0575All organisms (root)polo-like kinase 1 [EC:2.7.11.21],polo-like kinase 4 [EC:2.7.11.21],polo-like kinase 2 [EC:2.7.11.21]
FQ0S4Dikarya (subkingdom)cell cycle serine/threonine-protein kinase CDC5/MSD2 [EC:2.7.11.21],polo-like kinase 1 [EC:2.7.11.21]
KOG0575Eukaryota (superkingdom)polo-like kinase 1 [EC:2.7.11.21],polo-like kinase 4 [EC:2.7.11.21],polo-like kinase 2 [EC:2.7.11.21]
BMZETFungi (kingdom)cell cycle serine/threonine-protein kinase CDC5/MSD2 [EC:2.7.11.21],polo-like kinase 1 [EC:2.7.11.21]
9S5XTAscomycota (phylum)cell cycle serine/threonine-protein kinase CDC5/MSD2 [EC:2.7.11.21]
91MQ7Saccharomycetales (order)cell cycle serine/threonine-protein kinase CDC5/MSD2 [EC:2.7.11.21]
7JRKFOpisthokonta (clade)polo-like kinase 1 [EC:2.7.11.21],polo-like kinase 2 [EC:2.7.11.21],polo-like kinase 3 [EC:2.7.11.21]
AT4A6Saccharomycetaceae (family)cell cycle serine/threonine-protein kinase CDC5/MSD2 [EC:2.7.11.21]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: