Domains within Saccharomyces cerevisiae protein YMR232W

Alternative representations: 1 /

Protein length677 aa
Source databaseEnsembl
Identifiers YMR232W
Source gene YMR232W

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Fungi/Metazoa group

Predicted functional partners

YMR232W is shown as FUS2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for FUS2

Protein YMR232W is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04810Regulation of actin cytoskeleton

KEGG orthologous groups

KONameDescription
K05769ARHGEF4_29, ASEF1_2Rho guanine nucleotide exchange factor 4/29

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 10 PTMs annotated in this protein:

PTMCount
Phosphorylation10

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_133710.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YMR232W in eggNOG.

OGTaxonomic classDescription
FSI5DDikarya (subkingdom)dynamin-binding protein
LKOG3519All organisms (root)Rho guanine nucleotide exchange factor 4/29,dynamin-binding protein,T-lymphoma invasion and metastasis-inducing protein 1
KOG3519Eukaryota (superkingdom)Rho guanine nucleotide exchange factor 4/29,dynamin-binding protein,T-lymphoma invasion and metastasis-inducing protein 1
BMSHIFungi (kingdom)dynamin-binding protein
9S6M9Ascomycota (phylum)dynamin-binding protein
91HDKSaccharomycetales (order)RhoGEF
7M2EYOpisthokonta (clade)dynamin-binding protein,Rho guanine nucleotide exchange factor 38,SH3 domain-containing protein 19
AT4JBSaccharomycetaceae (family)RhoGEF

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: