Domains within Saccharomyces cerevisiae protein YMR276W

Alternative representations: 1 /

Protein length373 aa
Source databaseEnsembl
Identifiers YMR276W
Source gene YMR276W

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Fungi/Metazoa group

Predicted functional partners

YMR276W is shown as DSK2 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for DSK2

Protein YMR276W is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04141Protein processing in endoplasmic reticulum

KEGG orthologous groups

KONameDescription
K04523UBQLN, DSK2ubiquilin

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 4 PTMs annotated in this protein:

PTMCount
Phosphorylation3
Acetylation1

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_134140.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YMR276W in eggNOG.

OGTaxonomic classDescription
FPV1TDikarya (subkingdom)ubiquilin
LCOG5272All organisms (root)ubiquilin,UV excision repair protein RAD23,ubiquitin-small subunit ribosomal protein S27Ae
KOG0010Eukaryota (superkingdom)ubiquilin,ubiquilin-like protein,ubiquitin-like protein Nedd8
BMVPXFungi (kingdom)ubiquilin
9V0I8Ascomycota (phylum)ubiquilin
91NQJSaccharomycetales (order)ubiquilin
7MCMFOpisthokonta (clade)ubiquilin,ubiquilin-like protein
AT7PBSaccharomycetaceae (family)ubiquilin

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: