Domains within Saccharomyces cerevisiae protein YNR006W

Alternative representations: 1 /

Protein length622 aa
Source databaseEnsembl
Identifiers YNR006W
Source gene YNR006W

Domain architecture analysis

Display all proteins with similar:

Domain organisationProteins having all the domains as the query in the same order. Additional domains are allowed.
Domain compositionProteins with the same domain composition have at least one copy of each of the domains of the query.

This domain architecture was probably invented with the emergence of Ascomycota

Predicted functional partners

YNR006W is shown as VPS27 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for VPS27

Protein YNR006W is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04145Phagosome

KEGG orthologous groups

KONameDescription
K12182HGS, HRS, VPS27hepatocyte growth factor-regulated tyrosine kinase substrate

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 15 PTMs annotated in this protein:

PTMCount
Phosphorylation13
Ubiquitination2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_143160.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YNR006W in eggNOG.

OGTaxonomic classDescription
LKOG1818All organisms (root)hepatocyte growth factor-regulated tyrosine kinase substrate,zinc finger FYVE domain-containing protein 1,abscission/NoCut checkpoint regulator
FTIJEDikarya (subkingdom)hepatocyte growth factor-regulated tyrosine kinase substrate
KOG1818Eukaryota (superkingdom)hepatocyte growth factor-regulated tyrosine kinase substrate,zinc finger FYVE domain-containing protein 1,abscission/NoCut checkpoint regulator
BPGVBFungi (kingdom)hepatocyte growth factor-regulated tyrosine kinase substrate
9U6SVAscomycota (phylum)hepatocyte growth factor-regulated tyrosine kinase substrate
91FM9Saccharomycetales (order)hepatocyte growth factor-regulated tyrosine kinase substrate
7HRWUOpisthokonta (clade)hepatocyte growth factor-regulated tyrosine kinase substrate,targeting protein for Xklp2,large subunit ribosomal protein L7/L12
AT8TNSaccharomycetaceae (family)hepatocyte growth factor-regulated tyrosine kinase substrate

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: