Domains within Saccharomyces cerevisiae protein YOL128C

Alternative representations: 1 /

Protein length375 aa
Source databaseEnsembl
Identifiers YOL128C
Source gene YOL128C

Predicted functional partners

YOL128C is shown as YGK3 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for YGK3

Protein YOL128C is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04932Non-alcoholic fatty liver disease
map04360Axon guidance

KEGG orthologous groups

KONameDescription
K08852ERN1serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-]
K03083GSK3Bglycogen synthase kinase 3 beta [EC:2.7.11.26]

Post-translational modifications

PTM annotation is taken from PTMcode, a resource of known and predicted functional associations between protein post-translational modifications (PTMs). There are 2 PTMs annotated in this protein:

PTMCount
Phosphorylation2

To see the full details, including possible functional associations between the PTMs, please visit the PTMcode annotation page for protein AWRI1631_150320.

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YOL128C in eggNOG.

OGTaxonomic classDescription
FQGETDikarya (subkingdom)protein kinase MCK1,protein-serine/threonine kinase [EC:2.7.11.-]
LCOG0478All organisms (root)serine/threonine-protein kinase/endoribonuclease IRE1 [EC:2.7.11.1 3.1.26.-],RAC serine/threonine-protein kinase [EC:2.7.11.1],pto-interacting protein 1 [EC:2.7.11.1]
KOG0658Eukaryota (superkingdom)glycogen synthase kinase 3 beta [EC:2.7.11.26],kinase [EC:2.7.1.-],protein brassinosteroid insensitive 2 [EC:2.7.11.1]
BN9KTFungi (kingdom)protein kinase MCK1,protein-serine/threonine kinase [EC:2.7.11.-]
9SZMSAscomycota (phylum)protein kinase MCK1,protein-serine/threonine kinase [EC:2.7.11.-]
91EU4Saccharomycetales (order)protein kinase MCK1,protein-serine/threonine kinase [EC:2.7.11.-]
7HQVBOpisthokonta (clade)protein kinase MCK1,protein-serine/threonine kinase [EC:2.7.11.-]
AT5AUSaccharomycetaceae (family)protein kinase MCK1,protein-serine/threonine kinase [EC:2.7.11.-]

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: