Domains within Saccharomyces cerevisiae protein YPR106W

Alternative representations: 1 /

Protein length443 aa
Source databaseEnsembl
Identifiers YPR106W
Source gene YPR106W

Predicted functional partners

YPR106W is shown as ISR1 in the network

Click and drag to pan the network, and zoom by using your mouse wheel. Click the protein nodes for additional options.

The network on the left comes from STRING, a database of known and predicted protein interactions. Displayed here is the evidence view, where different line colors represent the types of evidence for the association.

Open the STRING annotation page for ISR1

Protein YPR106W is possibly involved in these pathways, based on its similarity to the listed KEGG orthologous groups:

KEGG pathways

PathwayDescription
map04912GnRH signaling pathway

KEGG orthologous groups

KONameDescription
K04428MAP3K4, MEKK4mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25]

Orthologous groups

Orthology information is taken from eggNOG, a database of orthologous groups of genes. Orthologous groups containing this protein are listed below. This protein is named 4932.YPR106W in eggNOG.

OGTaxonomic classDescription
FQBXQDikarya (subkingdom)Pkinase,PK_Tyr_Ser-Thr
LKOG4645All organisms (root)mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
KOG4645Eukaryota (superkingdom)mitogen-activated protein kinase kinase kinase 4 [EC:2.7.11.25],mitogen-activated protein kinase kinase kinase [EC:2.7.11.25]
BNNJDFungi (kingdom)Pkinase,PK_Tyr_Ser-Thr
9S9GRAscomycota (phylum)Pkinase
91J2ZSaccharomycetales (order)Pkinase
7M993Opisthokonta (clade)Pkinase,PK_Tyr_Ser-Thr
AT7I2Saccharomycetaceae (family)Pkinase

The SMART diagram above represents a summary of the results shown below. Domains with scores less significant than established cutoffs are not shown in the diagram. Features are also not shown when two or more occupy the same piece of sequence; the priority for display is given by SMART > PFAM > PROSPERO repeats > Signal peptide > Transmembrane > Coiled coil > Low complexity. In either case, features not shown in the above diagram are listed in the right side table below, and the reason for their omission is shown in the 'Reason' column.

Confidently predicted domains, repeats, motifs and features:

Outlier homologues and homologues of known structure:

Features NOT shown in the diagram: