Secondary literature sources for SCAN
The following references were automatically generated.
- Williams AJ, Blacklow SC, Collins T
- The zinc finger-associated SCAN box is a conserved oligomerization domain.
- Mol Cell Biol. 1999; 19: 8526-35
- Display abstract
A number of Cys(2)His(2) zinc finger proteins contain a highly conserved amino-terminal motif termed the SCAN domain. This element is an 80-residue, leucine-rich region that contains three segments strongly predicted to be alpha-helices. In this report, we show that the SCAN motif functions as an oligomerization domain mediating self-association or association with other proteins bearing SCAN domains. These findings suggest that the SCAN domain plays an important role in the assembly and function of this newly defined subclass of transcriptional regulators.
