SMART annotation of Monosiga brevicollis

This is the main page for the SMART annotation of Monosiga brevicollis genome. Use the Sequence analysis form below to display SMART bubblograms (graphical protein representations) for Monosiga proteins. You can use the full IDs (eg. jgi|Monbr1|97|gw1.5.16.1) or shorter version (in this case, 97 or gw1.5.16.1).

In addition, the 'Architecture analysis' form can be used to look for proteins containing a specific combination of domains using simple boolean logic (eq. you can query for 'TyrKc AND SH3' or 'TyrKc AND NOT SH2'). Protein intrinsic features can be included into the query (use the keyword SIGNAL for signal peptides and TRANS for transmembrane regions). To include Pfam domains into the query add 'Pfam:' in front of their name (eg. 'Pfam:PID AND TyrKc').

Download data files

• All predicted SMART and Pfam domains, signal peptides and transmembrane regions: monosigia_domains_features.gz
• SMART 'Schnipsel' database for Monosiga proteins: monosigia_schnipsel.fasta.gz
  "Schnipsel" is a German word meaning 'snippet' or 'fragment'. The schnipsel database consists of the sequences off all domains found with SMART. Outliers of a family often cannot be detected by a profile, yet are detectable by pairwise similarity to one or more established members of a sequence family. So, searching against the schnipsel database gives complementary information to the profile searches.
• Analysis of domain pairs in Monosiga and other Eukaryotes: domain_pairs.tar.gz
• Analysis of domain pairs (with species grouped into Metazoa - Non-Metazoa): domain_pairs_grouped.tar.gz
• Analysis of over and under represented Pfam domains in Monosiga versus human and S.pombe:
  1. including repeats (counting multiple hits per protein)
  2. excluding repeats (one hit per protein counted)